TISSUEscope™ 4000 scans 5"x7" Breast Tissue Slide


Using BPI’s latest instrument the TISSUEscope™ 4000 researchers at Sunnybrook Hospital, part of the University Health Network in Toronto, Ontario are now routinely scanning 5”x7” breast tissue slides as part of their ongoing research into breast cancer. The TISSUEscope™ 4000 has enabled the acquisition of large format images at higher pixel resolutions and with significantly fewer misalignment artifacts usually found in traditional microscope tiling systems. The overall workflow has been streamlined with the addition of a number of automation steps. The end result is an improvement to the overall image quality with a significant saving in time. 50 μm thick vibratome sections are stained with H&E and mounted whole on 5”x7” glass slides and then imaged with the TISSUEscope™ 4000. This example image is 142,603 x 105,000 pixels in size (41.8GB, original file size) and was scanned at a 1μm pixel resolution. Sample courtesy of Dr. Gina Clarke, Sunnybrook Health Sciences Centre, Toronto, Ontario. To view a high resolution representative breast tissue section click on the thumbnail image below.

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TISSUEscope™ 4000 New Product Launch


Biomedical Photometrics Inc. announces the launch of its latest generation of panoramic confocal fluorescence and brightfield slide scanners, the TISSUEscope™ 4000 for the pathology, medical research, genomics and general microscopy markets. The latest instrument comes equipped with 4 solid state fibre-coupled lasers as standard. This enables it to acquire images from slides stained with fluorescence markers such as DAPI/Hoechst in the violet, all the way into the far red (405, 488, 532 and 639 nm). Brightfield image acquisition has also been dramatically improved by adding a more efficient RGB detector system. The new TISSUEscope™ 4000 instrument comes with the latest version of the MACROview software, which now supports the industry standard BigTIFF image file format. Furthermore, the user interface has been streamlined and provides the instrument operator with a significantly more efficient workflow, substantially reducing image scanning set up time. With the addition of a 5" x 7" motorized stage the TISSUEscope™ 4000 offers researchers the flexibility to acquire a wide range of specimen sizes, all in stunning high resolution (0.5µm/pixel) detail. For more information and to download a product brochure click here.
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