Applications

Overview

Tissue Imaging

DNA Imaging

• Discover & validate novel biomarkers in fixed tissues
  
• Biomarker profiling
  
• Identify new drug targets
  
• Analyze subcellular functions
  
• Assess postgenomic translational modifications to identify new targets
  
• Analyze quantitative protein expression

• Correlate disease protein expression patterns with clinical outcome data
  
• Test biomarker expression on tissue microarrays with patient cohorts
  
• Compare and verify protein expression levels and patterns in animal model tissue vs. human disease counterpart
  
• Validate animal models for similarities in protein pathways of human disease
  
• Predictive toxicology
  
• Reveal protein variants underlying various tumor properties such as stage, aggressiveness, and drug response
  
• Reveal interaction of multiple simultaneous protein signaling pathways and proteomic patterns in diseased tissue
  
• High-throughput evaluation of associated with drug toxicity

• Develop & validate novel diagnostic reagents and tests corresponding to new biospecific therapeutics
  
• Target disease by subtype and biological class
  
• Allergy screening
  
• Autoimmune and inflammatory disease detection

• Revive or improve a failed investigational drug (discover subpopulations of drug efficacy)